Well, my character's personality isn't really as extreme as those above, but her design is certainly a crazy one.
She's a hybrid between canine and feline (on the canine model), born without eyeballs and simply skin over the concaves of where her eyeballs would be. Protein buildups resembling horns scatter her body, along with unkept tufts of fur. Massive ears with satellite hearing; she tends to click her tongue to navigate. Has vertical-aligned eye on her tongue that she can only use in the dark.
Her personality is a little toned down, to say the least.