Hmm, very odd. 'Ave ye tried running as administrator? That may fix y'er problem.
Also, try taking out the preset files and running FH then. If it does run, change y'er rendering system to Direct3D9 and put the files back in. To be honest, I'm a bit confused as to why this is happening. It could be a faulty file that corrupted when ye finished y'er preset?
Did it work fine before ye finished the preset? If so, double check y'er preset's files f'er anything out of the ordinary that shouldn't be there. It could be faulty coding.