Since MS Paint or Paint in general works under a bitmap format, it may not be compatible with the formats used for maps and other media like presets. I've actually tried before, but didn't get any results. Programs like Gimp and Photoshop can work because their more flexible than Paint. Added, you can manipulate images to different formats.
Then, I could be wrong, it was ages ago since I tried to it in Paint. Someone may correct me if I'm wrong.