I haven't tried a reinstall yet, I'm just tired of reinstalling just for another problem to effect my game and then another reinstall. It's a never ending cycle.
It really does suck - especially when it comes to the markings, items, and any other mods. But if you do reinstall, try it without any ENBs, podium mods, etc. Markings/Items should be fine, but it could be another mod effecting all of this.
If you do decide to do the reinstall, I'd backup the presets folders, markings.cfg/marking folder, and the same for items.